Employing the Biostat® D-DCU 10-3 it is demonstrated in this study, that this fermenter meets the requirements for an E. coli high-cell density fermentation.
Standardized Qualification of Biostat® D-DCU
The performance capabilities of a bioreactor, which are substantially influenced by its design and thus, its bioengineering characteristics, are crucial in order to choose a system matching the specific process requirements.
In order to guarantee a reliable comparison between existing bioreactor systems the DECHEMA guideline was published by an expert group as a standardized method required for the determination of the key bioengineering data.
Here the Biostat® D-DCU 30-3 and 100-3 are characterized according to this recommendation.