[ Webinar ]
Why Batch Can’t Match Multi-Column Chromatography: A Throughput Analysis
[ Overview ]
Biopharmaceutical manufacturers and CDMOs dealing with protein capture processes in a typical batch chromatography setting typically rely on expensive resins. To effectively balance material costs associated with resin investment, throughput is often rate-limited as a consequence. Larger columns/resin volume equate to higher throughput but also prove detrimental to factors such as facility footprint, and magnify as scale up to commercial production environments occur. The BioSMB platform, based on the principle of multi-column chromatography, minimizes the impact of throughput on column sizing. Using case studies of prior successes, this webinar explores how BioSMB multi-column chromatography increases throughput while reducing costs.
What You Will Learn
- Understand the limitations of single-column batch chromatography compared to multi-column systems.
- Highlight the benefits of BioSMB multi-column chromatography as an enabler of process intensification.
- Review case studies of BioSMB implementations to understand the real-world impact of multi-column chromatography.
- Explore multiple scenarios where BioSMB column cycling and continuous production enables increased throughput
while also managing resin utilization and cost
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