Characterization of bi-specific T-cell engager (BiTE) (2)

To develop the next new immunotherapy, you need to understand how immune cells affect tumor cells. By coupling live-cell analysis and advanced flow-cytometry workflows, a deep understanding of the biological mechanisms of immune cell activation and tumor cell killing, may be obtained.

This video brings to life a poster, showing the insights gained when combining the analytical powers of Sartorius’ Incucyte® Live-Cell Analysis, and iQue® advanced flow cytometry platforms.

The video depicts results from an experiment, characterizing immune cell killing induced by an α-hCD3xCD19 BiTE antibody.

The Incucyte® Live-Cell Analysis System allows dynamic analysis of immune cell killing through the capture of phase and fluorescent images and quantification of segmented objects.

#cellanalysis #cellculture #flowcytometry #livecellanalysis