Crossflow Filtration (also known as Tangential Flow Filtration, or TFF) is a filtration method used under dynamic flow conditions.
Product feed flows tangentially along the surface of the membrane where the product molecule is retained, while buffer and contaminants pass through the membrane. Sartorius Crossflow Ultrafilters contain Hydrosart TFF Membrane of various molecular weight cut-offs to manage volume reduction and buffer exchange in antibody, vaccine, and blood & plasma processes. Hydrosart is the preferred and best performing TFF membrane for biopharmaceutical manufacturing.