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Contribution of Preparative HPLC in Manufacturing From Small Molecules to Biologics

Larger-scale preparative HPLC was developed in the 1980s to maximize purity for therapeutic drugs by removing impurities of very close molecular structure. Now, HPLC is being used across modern modalities, including ADCs, peptides, and oligonucleotides.

In this webinar, Sartorius scientists explain the role of preparative HPLC in biopharmaceutical manufacturing. Learn about HPLC’s advantages, limits, and potential applications in the production of complex biologics. 

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What Will You Learn:

  1. Discover the levels of purity and yield you can achieve using preparative HPLC.

  2. Understand the expanding range of modalities suitable for HPLC purification.

  3. Learn how preparative HPLC system and columns are adapting to changes in the industry.

Meet Our Experts:

Yvan Ruland

Chromatography Specialist

Yvan is a chromatography specialist for the purification of active substances in pharmaceutical and biopharmaceutical industries at clinical and commercial scale. He holds a PhD in organic chemistry applied to biomolecules and has over 20 years of experience in the field of process optimisation and equipment’s supply for batch and multi column chromatography applied to small molecules purification and downstream intensification.


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