Single Cell, Clone & Colony Analysis, 선별 & Isolation
The CellCelector platform is a fully automated cell imaging and 채취 system developed for the 선별, selection and isolation of single cells, clusters, spheroids and organoids, as well as single cell clones and adherent colonies.
Based on the high scanning and 채취 speed which results in a fast retrieval of cells, the CellCelector is compatible with single cell RNA analysis applications and perfectly suited for the isolation of living cells. In combination with our Nanowell technology, the CellCelector is the perfect system for high-throughput 단일 세포 클로닝 or single B-cell secretion assays in antibody discovery, as well as the isolation of rare cells (e.g. CTCs) for subsequent analysis.
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Use our instrument configurator to design your very own customized CellCelector, perfectly tailored to meet your unique needs.
Fully automated image-based analysis, 선별, sorting and 채취 of single cells, clones, clusters and adherent cell colonies
Laminar flow cabinet with efficient control of temperature, humidity and CO2 level for long-term cloning experiments and live cell sorting
Parallel 선별 and isolation of thousands of cells for accelerating antibody discovery and 세포주 development
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Reusable stainless steel and glass capillaries & disposable plastic tips for CellCelector Flex
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The CellCelector inverted fluorescence microscope with high resolution optics allows the identification of target cells based on morphological attributes and fluorescence signals. The highly efficient imaging system offers a wide range of image processing options so that even similar cells can be differentiated.
Due to three different 채취 modules and compatibility with a huge range of 표준 and custom cell culture labware the CellCelector can be used in a multitude of research areas (e.g. 순환종양세포/CTC 선별, stem cell research as well as 세포주 development and antibody discovery).
The patented 채취 technology of the CellCelector is characterized by an extremely gentle cell transfer resulting in high cell integrity and outgrowth rates after 채취 (including up to 95% and more viability in 단일 세포 클로닝 applications).
The unique combination of a laminar 흐름 셀 culture hood and CO2 incubator allows keeping cells in stable environmental conditions during the experiments and provides optimal results and reproducibility.
Equipped with the Single Cell 채취 Module, the CellCelector provides gentle aspiration with extremely high precision down to the nanoliter range. Typical 어플리케이션 areas are:
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Fast generation of clonal pharmaceutical production cell lines with the CellCelector 단일 세포 클로닝 Technology:
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Single cell analysis with the CellCelector allows the detection of rare antibodies with unique properties which are hard to find under conventional 선별 methods. The system combines selective cell 선별, imaging, sensitive single cell secretion assays as well as cell isolation. Hundred-Thousands of cells can be processed in parallel. Individual cells will be screened immediately in specific and multiplexed immunoassays instead of culturing for weeks to reach a minimum number of cells for the assay.
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The CellCelector, with its specifically designed 채취 modules for adherent cells and cell colonies as well as for isolation from 반고체 배지 is extremely gentle, very specific and therefore ideally suited for the clonal passaging of stem cells, stem cell colonies as well as the isolation of specific parts of a stem cell colony. It will support your stem cell research, for example by:
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Practitioner insights in leveraging CellCelector applications, including 세포주 development, single cell isolation, stem cell research.
Yes, the CellCelector can isolate both living and fixed cells.
In order to recover cells from a dried surface it should be first pre-wet in PBS (e.g. 24 hours in advance) as cells are recovered using controlled liquid aspiration.
There is no intrinsic dead volume and corresponding cell loss during cell recovery.
The CellCelector can be placed in a biosafety cabinet (yours or a customized one, provided by 싸토리우스) or in our Incubator FlowBox. The latter does not only provide a sterile environment but also temperature, CO2 and humidity regulation and thus supports the cultivation of sensitive cells.
No. The CellCelector is equipped with a powerful robot arm that can potentially harm users. To protect them, the CellCelector must be installed within 하우징 with a safety lock. At the moment the 하우징 is open, the safety lock cuts immediately the motor's power. All housings offered for the CellCelector are equipped with such a safety lock. For applications which don’t need sterility we offer the CellCelector PCR Hood.
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