The ability to accurately and efficiently assess cell health is crucial in research and drug discovery. The need for characterizing apoptosis and apoptotic processes occurs throughout the drug discovery process, from primary screening to toxicity profiling. The value of simultaneous detection of multiple markers in different apoptotic pathways enables the ability to create apoptotic “profiles” for the compounds in a screening campaign, enabling researchers to make more informed decisions.

This application highlights the ability of advanced flow cytometry and the iQue® Human Apoptosis 4-Plex Kit to: 

• Detect and confirm apoptosis through different pathways using the mix and match reagents.
• Gain a robust determination of apoptosis progression and insight into the mechanism of action.

Simple mix-and-read 96 and 384-well protocol with no washing and no fixing.

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