Trusted cell characterization, quality assurance, and quality control
As CAR-T therapy development progresses, cell characterization and safety measures must be implemented and documented thoroughly. It is vital to continually ensure cellular identity and function. Cell cultures must also be verified to be free from contaminants. These processes are often time-sensitive, and classical sterility testing takes a long time, so an additional rapid solution is important. Real-time 선별 and analysis solutions provided by 싸토리우스 enable continuous phenotypic & functional analysis over time, and contaminant-free systems coupled with rapid testing options help ensure safety.
Don’t compromise your ambition. Gain trust in your cell characterization efforts by using the best equipment and software available. The Incucyte® Live-Cell Analysis System allows you to continually visualize and analyze the health and integrity of your cell cultures while the Intellicyt® iQue3 enables characterization efforts rapidly and with minimal sample volumes. The Virus Counter® Platform can be used to continue to assess the quality and quantity of your viral particles to support process development. Microsart® ATMP rapid real-time PCR mycoplasma and bacterial detection kits enable fast, easy contaminant detection for assurance of patient safety prior to treatment.
Rapid, highly specific & sensitive method providing fast contaminant detection during CAR-T cell characterization. Unique and highly specific TaqMan® qPCR assays are validated according to the International Pharmacopeia and increase patient safety prior to treatment.
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Automatically capture and analyze images of living 2D and 3D cell cultures. Get real time visualization of immune-cell killing assays, cell health, and viability. Assess antibody mediated phagocytosis, immune cell mediated 세포자멸사, and T cell proliferation & clustering without disturbing cells.
White papers:
Scientific Posters:
Achieve fast, reliable analysis of your in vitro assay readouts with the iQue® 3. The combination of speed and miniaturization, with powerful multi-parametric data analysis and visualization, gives you actionable results from a few microliters of sample, in record time.Screen for immune cell killing, 사이토카인 profiling, and more. Perform 세포독성 assays easily, quickly, and reproducibly.
어플리케이션 Notes:
Reliability of an assay depends strongly on the preparation phase. The programmable electronic pipette Picus reduces variability between users. Selecting a multichannel pipette will speed up your work and improve cell well-being by reducing the time outside the incubator. Both electronic Picus and manual Tacta pipettes guarantee the best pipetting ergonomics.
적용분야 노트:
CAR-T 바이러스 벡터 quantification has never been easier or faster. Measure total virus particles quickly and reproducibly to enable in vitro assays. ViroTag® 노워시 assays for lentivirus, AAV, and other viruses minimize variability and enable confidence over traditional methods.
Brochure:
View webinars, eBooks, infographics, literature and other educational material in our CAR-T Discovery & Development Resources area.
Frontiers in Cancer Immunotherapy
Discover how cytometry enables you to expedite CAR-T discovery.
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