Setting the 표준 in Immune 세포 치료제, Together
Immune cell therapies are a major advancement in the fight against blood cancers. While most of today’s commercialized therapies use harvested patient cells, increasing demand calls for 동종유래 solutions — and developers need robust processes that can scale up, maintain potency, and reduce cost per dose.
Bring your immune 세포 치료제 to market faster and more affordably with end-to-end solutions that deliver reproducible performance and scalability with a simplified path to regulatory approvals.
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Explore immune 세포 치료제 solutions to simplify progress in every step of your workflow.
: Media handling is complex, and unwanted impurities risk contaminating your media or buffer.
: Simplify, automate, and de-risk your media and buffer preparation processes.
Highlighted products|services:
: Make your aseptic filling 10X faster with our plug-and-play aliquoting solution.
: automated and GMP-compliant welding of PVC and TPE tubing with small diameter commonly used in CGT processes.
: Ensure sterile filtration using sterilizing-grade heterogeneous double-layer filters available in 0.8 and 0.45 μm pre-filter and a 0.2μm 최종 필터 membrane.
: Mitigate viral contamination using a viral retention filter designed for cell culture media.
: Comply with regulatory requirements using services backed by more than 25 years of industry experience.
: Support all fluid handling and transportation steps for drug manufacturing from 20 mL to 3,000 L.
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: Cells exhibit low viability, low recovery, and reduced functionality during isolation and activation processes.
: Confidently isolate, preserve, and activate your immune cells using high-performing reagents.
Highlighted products:
: Simplify your process, reduce serum-associated risks, and ease regulatory procedures using media designed and optimized for culturing immune cells.
: Choose from a variety of high-quality cytokines trusted by scientists in immune 세포 치료제.
& cryopreservation media: Enable short- and long-term cryopreservation that provides high performance and recovery after freezing.
: Support your therapy development with commercially available, high-quality, and animal and human origin-free recombinant human albumins.
: Today’s gene editing technologies and delivery tools have 제한 precision and efficiency.
: Simplify and tailor your process for non-viral gene delivery and transduce your cells with high-quality vector using our lentivirus solutions.
: Scientists need to achieve efficient, consistent, and scalable expansion of target cell types while maintaining cell viability and functionality.
: Achieve robust and scalable expansion of a variety of target cell types - including T cells, Tregs, TILs, dendritic cells, and natural killer cells — with a wide selection of advanced equipment and high-quality raw materials and reagents.
, and single-use bioreactors: Achieve automation and high throughput with single-use commercial-scale bioreactors. For processes requiring GMP compliance, we recommend the Biostat STR® bioreactor.
: Manually identifying and optimizing critical process parameters and quality attributes during development and scale-up is inefficient and time-consuming.
: Enable fast, accurate, and robust process control using optimized analytics, including design of experiments (DOE) and 다변량 데이터 분석 (MVDA) software.
software: Accelerate progress by quickly tapping into the power of DOE.
software: Improve process understanding, model complex systems, and gain the deep process understanding needed to drive growth.
: Monitor the effects of feed strategy and media components on cell culture performance.
: Scientists need to maintain sterility and cell quality during harvest while maximizing cell yield and viability.
: Reliably harvest and wash immune cells using fast, high-performing, and scalable solutions that ensure high yield, viability, and quality.
systems: Deliver high cell viability and recovery using single-use and low shear counterflow centrifugation systems.
: Support your therapy development with commercially available, high-quality, and animal- and human-origin-free recombinant human albumins.
bags: Protect critical fluids throughout production with extensively qualified bags for cell and 유전자 치료제.
: Thawing and storage risk reducing cell recovery and viability.
: Ensure high recovery and viability with controlled freeze-thaw processes, optimized cold storage, and validated shipping solutions for long- and short-term storage and transportation of sensitive cells.
To help find the right materials and consumables for your needs, request a sample from our portfolio.
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Optimize your cell and 유전자 치료제 process with expert development support—from early stages to scale-up—for efficiency, consistency, and compliance.
Ksep® empowers next-generation cell therapies with gentle, single-use automated centrifugation technology.
Stabilize your immune 세포 치료제 with versatile recombinant human albumin.
Protect your product during storage and shipping for sterile filtration, media preparation, sampling, and fluid transfer steps.
Optimize your CPPs and CQAs quickly with multi-parallel and semi-automated mini-bioreactors.
Preserve sterility and protect your process from virus contamination with reliable filters for media and buffer filtration.
분액 your media and buffers 10x faster while minimizing variability with a ready-to-use automated aliquoting system.
Ensure robust proliferation and differentiation with seamless scale-up with preclinical-grade and GMP cytokines.
Preserve your cells with animal component-free solutions for short- and long-term storage.
Achieve high cell yield and viability with scalable and widely compatible media.
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Immune 세포 치료제 manufacturing is the process of producing a immune 세포 치료제 medicinal product. Immune cell therapies have applications primarily in oncology and autoimmune diseases.
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The most prominent types of immune cell therapies are T cells that are genetically engineered to express chimeric antigen receptors (CARs) or T cell recepters (TCRs), and tumor infiltrating lymphocytes (TILs). The other cell types include natural killer (NK) cells and dendritic cells (DCs).
싸토리우스 provides GMP and automated tools with comprehensive analytics software. Our automated bioreactors use a design of experiments approach to accelerate optimization. We also provide high-quality raw materials suitable for GMP-grade manufacturing, available in a variety of sizes and packaging. Our goal is to enable immune 세포 치료제 developers to achieve reproducible performance at all scales.
Learn how CAR-T 공정 집적화 can support higher cell densities, enabling seamless scale-up and reducing process development costs.
This 게시물 features research on developing, optimizing, and intensifying CAR-T processes in stirred tank bioreactors (STRs).
Learn how combining CellGenix® cytokines can save you time and costs.
Explore the use of CellGenix® GMP T cell medium and cytokines for generating CAR-T cells with an early differentiated memory T cell phenotype.
Discover methods for growing and enhancing CAR-T cells in automated stirred-bioreactors.
Read about using Ambr® 15 cell culture time- and cost-efficiently to establish T cell culture in stirred conditions and screen various types of media.
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